HomePhysiciansAristides Assimacopoulos, MD, FIDSA, FACP

Aristides Assimacopoulos, MD, FIDSA, FACP

Philosophy of Care

The doctor is there to help the patient make their quality of life better in as much as that is possible. That often means prescribing medications. However, simply starting a medication is not always the best solution to every problem. I try to listen and understand what is actually important to the patient and try to get the real root of the problem. If a non-medication solution is possible and appropriate, this is preferable. Open and honest communication between doctor and patient is very important, even if they don’t agree on everything. I offer patients advice based on current medical knowledge and try to maintain a healthy skepticism about standard medical advice. Medicine and health are not “one size fits all.” My patients get the same advice that I would give my own family member. I don’t mind admitting that I don’t know something and will take the time to find new or updated information.

Patient Satisfaction Rating

Based on 279 reviews

  • General


    • Internal Medicine


    • Infectious Disease
    • Internal Medicine

    Accepts adults


    • English
    • Greek

    Adult/Internal Medicine, Infectious Disease, HIV, Hepatitis C and Telemedicine

    Family, Japanese karate and Byzantine music

  • Education

    School University of Minnesota
    Graduation Date 06/1991
    Degree MD

    School University of Minnesota
    Title Resident in Internal Medicine

    School University of Minnesota
    Specialty Infectious Disease

  • Memberships

    • American College of Physicians
    • Infectious Disease Society of America
  • Awards and Accolades

    Name Fellow of the Infectious Disease Society of America
    Date 09/2004

    Name Fellow of the American College of Physicians
    Date 09/2004

  • Media/Published Articles

    • Turtinen LW, Assimacopoulos AP, Haase AT. Increased monokines in cytomegalovirus infected myelomonocytic cell cultures. Microbial Pathogenesis 1989; 7: 135-145. • Schlievert PM, Assimacopoulos AP, Cleary PP.
    • Severe invasive group A streptococcal disease: clinical description and mechanisms of pathogenesis. Lab Clin Med 1996;127:13-22. • Assimacopoulos AP and Schlievert PM.
    • Staphylococcal and streptococcal toxic shock and Kawasaki syndromes. In: Schlossberg D, ed. Current Therapy of Infectious Disease. St. Louis: Mosby-Year Book, 1996. • Wagner JG, Schlievert PM, Assimacopoulos AP, Stoehr JA, Carson PJ, Komandina K.
    • Acute group G streptococcal myositis with streptococcal toxic shock syndrome: case report, microbiology, and review of the literature. Clin Infect Dis 1996;23:1159-61. • Kim MA, Assimacopoulos AP, Schlievert PM.
    • Polymerase chain reaction amplification & southern hybridization detection of streptococcal pyrogenic exotoxins. In: Persing DH, ed. PCR Protocols for Emerging Infectious Diseases. Washington, DC: American Society for Microbiology, 1996. • Assimaco
    • Mitogenic Factors from Group G Streptococci Associated with Scarlet Fever and Streptococcal Toxic Shock Syndrome. In: Streptococci and the host. Proceedings of the XIIIth Lancefield International symposium on streptococci and streptococcal diseases.
    • Staphylococcal and streptococcal toxic shock and Kawasaki syndromes. In: Kassirer JP and Green HL II, eds. Current Therapy in Internal Medicine. St. Louis: Mosby-Year Book, 1997. • Schlievert PM, Dunny GM, Stoehr JA, Assimacopoulos AP.
    • Aggregation and binding substances enhance pathogenicity in a rabbit model of enterococcus faecalis endocarditis. Adv Exp Med Biol 1997;418:789-91. • Assimacopoulos AP, Stoehr JA, Schlievert PM.
    • Mitogenic factors from group G streptococci associated with scarlet fever and streptococcal toxic shock syndrome. Adv Exp Med Biol 1997;418:109-14. • Schlievert PM, Gahr PJ, Assimacopoulos AP, Dinges MM.
    • Aggregation and binding substances enhance pathogenicity in rabbit models of enterococcus faecalis endocarditis. Infect Immun 1998;66:218-23. • Roggiani M, Assimacopoulos AP, Schlievert PM.
    • Exotoxins of Streptococcus pyogenes. In: Stevens DL and Kaplan EL, eds. Streptococcal Infections. New York: Oxford University Press, Chapter 4, pp57-75, 2000. • Assimacopoulos AP and Schlievert PM.
    • Staphylococcal and streptococcal toxic shock and Kawasaki syndromes. In: Schlossberg D, ed. Current Therapy of Infectious Disease. St. Louis: Mosby-Year Book, 2000. • Patrick M. Schlievert and Aristides P Assimacopoulos.
    • Toxic Shock Syndrome (Chapter 181) p 1578, In: Gorbach S, Bartlett JG, eds. Infectious Diseases, 3rd Edition, Lippincott Williams & Wilkins. 2003 • Assimacopoulos AP and Schlievert PM.
    • Staphylococcal and streptococcal toxic shock and Kawasaki syndromes. In: Schlossberg D, ed. Current Therapy of Infectious Disease. St. Louis: Mosby-Year Book, 2008 • Assimacopoulos AP.
    • Epidural Abscess, Discitis and Vertebral Osteomyelitis caused by Neisseria subflava. South Dakota Medicine 2007:60(7);265-269 • Aristides Assimacopoulos MD, Rabiul Alam MD, Manual Arbo MD, Jawad Nazir MD, Deng-Geng Chen Ph.D, Susan Weaver MSN CNP, Ma
    • A Brief Retrospective Review of Medical Records Comparing Outcomes for Inpatients Treated Via Telehealth Versus In-Person Protocols: Is Telehealth Equally Effective as In-Person Visits for Treating Neutropenic Fever, Bacterial Pneumonia, and Infected
    • Improving Cleaning of the Environment Surrounding Patients in 36 Acute Care Hospitals. Infection Control and Hospital Epidemiology 2008; 29:1035-1041 (Participated as a member of the Study Group through Avera McKennan Hospital, Sioux Falls, South Dak
    • Extreme Pyrexia and Rapid Death Due to Staphylococcus aureus Infection: Analysis of 2 Cases. Clin Infect Dis 2009;48:612- 4. • Yasir Lal and Aristides P. Assimacopoulos.
    • Two Cases of Daptomycin-Induced Eosinophilic Pneumonia with Chronic Pneumonitis. Clin Infect Dis 2010;50:737-740. • Johnson, JR et. al. and the MASTER Investigators.
    • Comparison of Eschericia coli ST131 Pulsotypes, by Epidemiologic Traits, 1967-2009. EID 2012;18(4):598. • Aris P Assimacopoulos, et al.
    • Post-Prostate Biopsy Infection with Escherichia coli ST131 Leading to Epididymo-orchitis and Meningitis Caused by Gram-Negative Bacilli. J Clin Microbiol 2012, 50(12):4157. • Aristides P Assimacopoulos, Wilmara Salgado-Pabon, Patrick M Schlievert.
    • Staphylococcal and streptococcal toxic shock and Kawasaki syndromes. In: Schlossberg D, ed. Clinical Infectious Disease. Second Edition. Cambridge University Press. 2015 PRESENTATIONS American Telemedicine Association, 11th Annual Meeting, May 7-10,
    • “Infectious Disease and Telemedicine” CME and Resident Lectures 1996-Present, St. Paul Infectious Disease Associates and Infectious Disease Specialists, PC • Various topics, incl., AIDS, Antibiotics, Hepatitis, Respiratory Tract Infections, Lyme Dise
    • XIIITH Lancefield International Symposium on Streptococci and Streptococcal Diseases; Pasteur Institute, Paris, France, Sept. 17, 1996 • Aristides P Assimacopoulos and P.M. Schlievert
    • Mitogenic factors from group G streptococci associated with scarlet fever and streptococcal toxic shock syndrome. Oral communication • P.M. Schlievert, G.M. Dunny, Aristides P. Assimacopoulos.
  • Research & Clinical Trials


    • Microbial pathogenesis of streptococci, staphylococci, and enterococci 1995 – 1996 Fellowship in Infectious Disease University of Minnesota, Dr. Patrick M. Schlievert, Department of Microbiology, Advisor
    • PCR analysis of a Murine model of Toxoplasmosis 1992 – 1993 Internal Medicine Residency CRC Rotation University of Minnesota, Dr. Claire Pomeroy, Minneapolis VAMC, Division of Infectious Disease, Advisor
    • Cytokine induction of Human Cytomegalovirus 1986 – 1987 Undergraduate Honors Thesis University of Minnesota, Dr. Ashley T. Haase, Professor and Chairman, Department of Microbiology, Advisor
    • HIV Care Management 2011-2012 State Grant for Care Management services to HIV patients State of South Dakota, Participated as member of team from Infectious Disease Specialists, PC to procure this Grant and provide services to patients

  • Patient Ratings & Comments

    Patient Satisfaction Rating
    Based on 279 reviews

    Rating Categories

    The Patient Satisfaction Rating score is an average of all responses to care provider related questions on our independent rating system, the Press Ganey Patient Satisfaction Survey.

    Responses are measured on a scale of 1 to 5, with 5 being the best score. Learn more about our patient satisfaction survey.

    Press Ganey Certified Data Integrity

    Ease of scheduling appointments

    278 ratings

    Provider showed concern

    279 ratings

    Provider explained things clearly

    278 ratings

    Provider included you in decisions

    274 ratings

    Likelihood of recommending this provider

    275 ratings

    Comments (30)

    Comments are collected in our Press Ganey Patient Satisfaction Surveys. Patients are de-identified to protect confidentiality and patient privacy. Learn more about our patient satisfaction survey.

    Oct 31, 2019
    *Dr. Assimacopoulos gave me good advice and instruction. He is very personable and I trust his advice.   
    Oct 27, 2019
    Dr. Assimacopolous is absolutely a great doctor in every way!He has done so much to keep me well I will be forever great full to him. your office is extremely lucky to have him.   
    Oct 14, 2019
    Dr A. was fantastic! First time meeting him for a physical but I had a few other concerns he addressed. He was incredibly attentive, spent a lot of time with me. He fixed a few See more  
    Oct 07, 2019
    *Dr. Assimacopoulos is a very intelligent and caring doctor. He listened & thoroughly and very well _____ my concerns & conditions. I will continue to see *Dr. Assimacopoulos.  
    Sep 25, 2019
    all good  
    Sep 24, 2019
    Dr. Assimacopoulos is easily one of the best doctors I have ever seen. He is extremely approachable, friendly, professional and extremely competent.  
    Sep 23, 2019
    Dr. A is fantastic!  
    Sep 18, 2019
    Dr. A is a compassionate and caring physician that I have recommended to many. He respects his patients and I always feel that he and I are working together as a team to better my See more  
    Sep 03, 2019
    Dr A was right on in his diagnosis  
    Aug 13, 2019
    Dr. Assimacopolous is a very personable guy. He listened to all of my concerns, answered all of my questions and never rushed me.  
    Jul 30, 2019
    best Doc  
    Jul 28, 2019
    Dr. A is kind and professional.  
    Jul 16, 2019
    *Dr. A. is very thoughtful, skilled & caring.  
    Jul 02, 2019
    very good communication from Dr A, and answered all my questions with no rushing. Very Happy  
    Jul 02, 2019
    I like Dr A he was friendly and answered my questions  
    Jun 16, 2019
    Excellent care provider and recommend to others.  
    Jun 12, 2019
    Jun 05, 2019
    Dr. Assimacopoulos is the best!  
    May 01, 2019
    I have recommended him to some of my friends and family.  
    Apr 19, 2019
    Doctor A. is terrific.  
    Apr 16, 2019
    Good experience  
    Apr 10, 2019
    This was our first time seeing this doctor. Both my husband and myself were very pleased with the doctor and look forward to having him be our provider.  
    Mar 21, 2019
    Mar 10, 2019
    excellent physician. we are very pleased with him.he is very efficient and personable.  
    Mar 05, 2019
    Overall excellent provider who has experience and has my confidence.  
    Mar 03, 2019
    Excellent doctor!! goes above and beyond  
    Feb 05, 2019
    I feel very comfortable with Dr.A - which is a very positive quality with my doctor.  
    Feb 02, 2019
    Dr. A is a great guy. Never any issues! Thanks for keeping me healthy.  
    Jan 20, 2019
    I have recommended him. always willing to listen and give different options.  
    Dec 07, 2018
    Dr A is cool!  
    (Viewing 10 of 30)
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Health Topics Posts
By Anthony Peterson, MD, FAAD, Aristides Assimacopoulos, MD, Brian Kadow, MD, Ethan Kosova, MD, MPH, Marc Fallah, MD, FAASLD, Matthew Baugh, MD, Paul Signorino, MD, FACS, Shakaib Hayat, DO, Zeeshan Ali, MD
Did you know that men are at an increased risk of developing a variety of health conditions including gout, a hernia or liver disease? During the month of November, in an effort to increase awareness of many of the health conditions that impact men’s health, our team of experts share tips to reduce your risk and stay healthy.

Topics and Subtopics: General Health, Men's Health & Senior's Health
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